Marburg virus outbreaks in Africa

Ebola virus outbreaks in Africa: past and present.

Ebola haemorrhagic fever (EHF) is a zoonosis affecting both human and non-human primates (NHP). Outbreaks in Africa occur mainly in the Congo and Nile basins. The first outbreaks of EHF occurred nearly simultaneously in 1976 in the Democratic Republic of the Congo (DRC, former Zaire) and Sudan with very high case fatality rates of 88% and 53%, respectively. The two outbreaks were caused by ...

Etymologia: Marburg Virus

Marburg Virus Disease

formation and transduction mechanisms are in dispute and remain to be investigated witlh renewed vigor. Lysogenic conversion may be operative in the myco-bacteria. Six of the papers are devoted to the study of lysogenic mycobacteria, whiclh exlhibit plhenotypic clhanges suclh as cell-wall alterations (expressed as chaniges in eitlher cell or colony morplhology), altered enzymatic activity, and ...

Marburg Virus Reverse Genetics Systems

The highly pathogenic Marburg virus (MARV) is a member of the Filoviridae family and belongs to the group of nonsegmented negative-strand RNA viruses. Reverse genetics systems established for MARV have been used to study various aspects of the viral replication cycle, analyze host responses, image viral infection, and screen for antivirals. This article provides an overview of the currently est...

Forty years of marburg virus.

Forty years ago, in early August 1967, the first filovirus ever detected, Marburg virus, made its appearance in Europe, causing severe and often fatal hemorrhagic fever in laboratory workers in Marburg and Frankfurt and, about 4 weeks later, in Belgrade. The etiological agent was isolated and identified by the combined efforts of virologists in Marburg and Hamburg within the very short time of ...